Stem Cells and Chronic Liver Disorders

Stem Cells and Chronic Liver Disorders

Chronic liver disorders affect millions of people and result in about two million deaths each year. When a liver transplant is not an option, stem cell treatment can prove beneficial to patients suffering from various chronic liver disorders.

A recent article showed that stem cell-based interventions provide significant improvement in patients who suffer from chronic liver disorders,like chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.The article indicated that stem cells play a vital role in “hepato-protection process by some mechanisms involving anti-inflammatory, auto-immune-suppression, angiogenesis and anti-apoptosis. Further, studies indicated that SCs derived paracrine factors promote angiogenesis, reduce inflammation and inhibit hepatocyte apoptosis.”

The review article also highlights that the following types of stem cells can be used in the treatment of liver disorders.

  • Stem Cell-Derived Hepatocytes – Stem cells can transform into hepatocyte-like cells using various growth factors.These cells can offer symptomatic relief to patients suffering from liver disease.
  • Bone Marrow-Derived Stem Cells – Stem cells derived from bone marrow have been found to be therapeutic forliver cirrhosis patients. These stem cells fuse with mature liver cells, and transfer materials that stimulate cell regeneration.
  • Mesenchymal Stem Cells – Mesenchymal Stem Cells exist throughout the body but those found in the adipose or fat tissue are known to be the highest quality. These stem cells are highly effective in providing symptomatic relief in liver cirrhosis patients.

The review clearly points out that stem cell-based treatments provide noticeable improvements in patients with chronic liver disorders.

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