24 Nov Stromal Vascular Fraction Therapy
Stromal vascular fraction (SVF) is a newer form of stem cell therapy that uses stem cells harvested from adipose tissue (fat) in our bodies.
These naturally occurring stem cells in the adipose tissue have powerful healing properties because they produce growth factors, and differentiate into mesenchymal stem cells, endothelial precursor cells, T-regulatory cells, macrophages, smooth muscle cells, pericytes, preadipocytes, etc. These growth factors not only help differentiate stem cells into specific cells that replace body’s damaged cells but also influence other pathways of tissue growth, healing, and optimized function.
SVF has possible uses in curing a wide range of inflammatory and degenerative diseases, some of which include rheumatoid arthritis, osteoarthritis, Crohn’s disease, ALS, Parkinson’s Disease, Migraine, Diabetes, etc. SVF is a novel approach and will be reserved for cases where all conventional therapies have failed.
SVF differs from other alternative medical treatments in that it not only cures by reversing pathophysiologic processes but also improve age-related decline of the cells. SVF reduces total treatment time and improves the quality of life for patients with chronic pain and disease.
It’s important to optimize your immune system prior to SVF. This is supposed to increase the quality of your stem cells and your body’s ability to self-regulate.
Early scientific evidence
Evidence is beginning to pile up on the safety of SVF in various ways stem cells can be used therapeutically. Trials are underway that are assessing their efficacy in a wide range of diseases.
SVF has been tested as a therapy for baldness, whereby it works by stimulating the patient’s dormant hair follicles to produce healthy hair.
In a recent study, SVF was used for degenerative diseases in orthopedics, neurological conditions and systemic conditions. The body fat was aspirated and processed and delivered intraarticularly, intravenously, intrathecally, or intradiscally directly into each patient. The results showed that it a completely safe procedure with no adverse events, except for mild and transient soreness at the site of liposuction and occasional headache.
In another study, patients’ body fat was extracted, processed and injected into the knee joint. The results showed that patients reported a reduction in pain levels after 3 months, and the procedure was shown to be safe and with no severe adverse events or complications.
SVF is thought to be safe in that only the patient’s own fat is used, and that there is no cord blood or embryonic stem cells in this procedure. SVF is as an easily accessible and usable source of regenerative cells with therapeutic potential in many diseases.
However, it is important to note that while early scientific evidence for it safety is beginning to accumulate, large studies are required to prove its efficacy. FDA is careful in promoting research and assessing evidence before stem cell therapies can be widely accepted and used in clinical settings. Until then, they majorly remain experimental.